Adrafinil is an orally-administered nootropic research compound that is metabolised in the liver to modafinil. Unlike injectable peptides, adrafinil is supplied in capsule or powder form for oral administration — the universal calculator below handles powder-weight dosing maths if you need to compute per-administration amounts from a bulk powder.
For research and educational purposes only. This calculator performs volumetric mathematics on the values you enter; it does not recommend doses or provide medical advice.
Universal peptide & nootropic dose calculator
Standard research pen format: 3 mL total volume, 300 clicks per pen. That’s fixed — so the only thing that changes is how many mg are in your specific pen. mg per click = your pen’s mg ÷ 300.
Vial mode: for lyophilised powder vials you reconstitute yourself with bacteriostatic water. Tell us the vial mg, how much BAC water you added, and your target dose — we work out the exact volume to draw on a U-100 insulin syringe.
Research and educational purposes only. Not medical advice. Not for human consumption. This calculator performs volumetric mathematics on the values you enter; it does not recommend doses. Compounds listed are not licensed as medicines for human use unless stated otherwise.
About Adrafinil
Adrafinil is a synthetic compound that acts as a prodrug for modafinil — once metabolised, the active compound in the body is modafinil. Adrafinil itself has never been licensed as a medicine in any jurisdiction (modafinil is a separately licensed prescription medicine in the UK). Adrafinil is supplied as a research-grade compound, primarily orally as capsules or bulk powder.
Published research literature has examined adrafinil and its metabolite modafinil in wakefulness, cognitive, and attention research. Adrafinil is the unscheduled precursor; modafinil is the licensed prescription medicine in the UK.
Typical reconstitution / pen formats
| Format | BAC water | Concentration / mg per click | Volume to draw / clicks | For |
|---|---|---|---|---|
| Capsule administration | — | Pre-measured per capsule | Typically 300mg or 600mg per capsule | for direct oral administration |
| Bulk powder | Powder weighing required | Variable | Use precise scale; common per-administration weights 300–600mg | for direct oral administration |
Adrafinil dosing observed in research literature
Reported research-literature dose ranges for adrafinil fall predominantly in the 300–900mg range per administration, with a once-daily morning administration pattern most commonly described.
These figures are reported here for completeness of the research-literature picture and do not constitute a dosage recommendation.
Half-life and frequency
Adrafinil itself has a short half-life (approximately 1 hour) as it is rapidly converted to modafinil in the liver. The active modafinil metabolite has a much longer half-life of approximately 12–15 hours, which is why adrafinil produces multi-hour wakefulness research effects despite its short native half-life.
Storage and shelf life
Adrafinil powder and capsules should be stored in a cool, dry place protected from light. Powder is generally stable at room temperature for the manufacturer’s stated shelf life.
Frequently asked questions
How is adrafinil administered in research?
Adrafinil is administered orally as capsules or in measured powder form. Subcutaneous and intranasal routes are not described in the established research literature.
Why use adrafinil instead of modafinil?
Adrafinil is unscheduled in many jurisdictions whereas modafinil is a licensed prescription medicine. Adrafinil produces its effects via conversion to modafinil but is more accessible as a research-grade compound.
Is adrafinil legal in the UK?
Adrafinil is unscheduled under the UK Misuse of Drugs Act 1971. It is not licensed as a medicine. Modafinil is a separately licensed prescription medicine in the UK — adrafinil and modafinil are not legally interchangeable.
What is the difference between adrafinil and modafinil?
Adrafinil is a precursor that is metabolised to modafinil in the liver. The end-state active compound in the body is the same. See our Modafinil information page for the licensed prescription medicine.
Related compounds and stacks
Where to source research-grade Adrafinil
For UK readers researching Adrafinil, our partner supplier stocks research-grade preparations. (Partner link to be added after the affiliate arrangement is signed.) We do not sell peptides ourselves and are not responsible for any third-party supplier’s product quality, regulatory compliance, or customer service.
Compliance: Stackcalc.co.uk provides calculator tools and information for research and educational purposes only. We do not sell, supply, or recommend peptides, nootropics, or any other compounds. Content on this site does not constitute medical advice. Always consult a qualified healthcare professional. Not for human consumption.