Calculator for the Ipamorelin + CJC-1295 combination — the most-researched growth-hormone-secretagogue stack in published literature. The combination is typically supplied as a pre-mixed pen or vial with equal mg of each compound.
For research and educational purposes only. This calculator performs volumetric mathematics on the values you enter; it does not recommend doses or provide medical advice.
Universal peptide & nootropic dose calculator
Standard research pen format: 3 mL total volume, 300 clicks per pen. That’s fixed — so the only thing that changes is how many mg are in your specific pen. mg per click = your pen’s mg ÷ 300.
Vial mode: for lyophilised powder vials you reconstitute yourself with bacteriostatic water. Tell us the vial mg, how much BAC water you added, and your target dose — we work out the exact volume to draw on a U-100 insulin syringe.
Research and educational purposes only. Not medical advice. Not for human consumption. This calculator performs volumetric mathematics on the values you enter; it does not recommend doses. Compounds listed are not licensed as medicines for human use unless stated otherwise.
About Ipamorelin + CJC-1295
Ipamorelin is a selective growth-hormone secretagogue (a synthetic pentapeptide that stimulates GH release). CJC-1295 is a long-acting analogue of growth-hormone-releasing hormone (GHRH). The two are commonly combined in research because they act on complementary GH-release pathways — ipamorelin via the ghrelin/GHS-R receptor, CJC-1295 via the GHRH receptor. Both are unscheduled under the UK Misuse of Drugs Act 1971 and are supplied as research-grade compounds.
Published research literature describes the Ipamorelin + CJC-1295 combination in growth-hormone research, body-composition research, and recovery research. The pulsatile-GH-release pattern produced by the combination is the subject of multiple research protocols.
Typical reconstitution / pen formats
| Format | BAC water | Concentration / mg per click | Volume to draw / clicks | For |
|---|---|---|---|---|
| 5mg + 5mg pen (3ml/300 clicks) | — | 0.033 mg/click of EACH compound | ≈9 clicks for 300mcg each / ≈6 clicks for 200mcg each | industry-standard combo pen |
| 5mg + 5mg vial | 2 mL BAC water | 2.5 mg/mL of EACH compound | 0.08 mL (8 units U-100) | for a 200mcg each administration |
| 5mg + 5mg vial | 3 mL BAC water | 1.67 mg/mL of EACH compound | 0.12 mL (12 units U-100) | for a 200mcg each administration |
Ipamorelin + CJC-1295 dosing observed in research literature
Reported research-literature dose ranges for the combination fall predominantly in the 100–300mcg of EACH compound per administration. Pre-sleep (evening) administration is the most commonly described pattern in published research, aligning with the natural endogenous GH-release window.
These figures are reported here for completeness of the research-literature picture and do not constitute a dosage recommendation.
Half-life and frequency
Ipamorelin has a short half-life (approximately 2 hours). CJC-1295 has a much longer half-life when modified with DAC (Drug Affinity Complex) — up to 6–8 days. The non-DAC variant (CJC-1295 No-DAC, sometimes labelled Mod-GRF-1-29) has a much shorter half-life (~30 minutes).
Storage and shelf life
Lyophilised refrigerated; reconstituted approximately 28 days refrigerated.
Frequently asked questions
Why combine Ipamorelin and CJC-1295?
The two compounds act on complementary pathways — ipamorelin via the GHS-R (ghrelin) receptor, CJC-1295 via the GHRH receptor. Combined administration is described in research literature as producing a more substantial pulsatile-GH-release pattern than either compound alone.
What is the difference between CJC-1295 with DAC and without DAC?
DAC (Drug Affinity Complex) is a modification that dramatically extends CJC-1295’s serum half-life from minutes to days. With-DAC CJC-1295 produces sustained elevated GHRH activity; without-DAC CJC-1295 (Mod-GRF-1-29) produces brief pulses aligned with the natural GHRH-release pattern.
When is the combination typically administered in research?
Pre-sleep (evening) administration is the most commonly described pattern, aligning with the natural endogenous GH-release window.
Is the Ipamorelin + CJC-1295 combination legal in the UK?
Both compounds individually are unscheduled under the Misuse of Drugs Act 1971. The combination is supplied as research-grade. Neither is licensed as a medicine in the UK.
Related compounds and stacks
Where to source research-grade Ipamorelin + CJC-1295
For UK readers researching Ipamorelin + CJC-1295, our partner supplier stocks research-grade preparations. (Partner link to be added after the affiliate arrangement is signed.) We do not sell peptides ourselves and are not responsible for any third-party supplier’s product quality, regulatory compliance, or customer service.
Compliance: Stackcalc.co.uk provides calculator tools and information for research and educational purposes only. We do not sell, supply, or recommend peptides, nootropics, or any other compounds. Content on this site does not constitute medical advice. Always consult a qualified healthcare professional. Not for human consumption.