Calculator for MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) reconstitution and per-administration dosing maths.
For research and educational purposes only. This calculator performs volumetric mathematics on the values you enter; it does not recommend doses or provide medical advice.
Universal peptide & nootropic dose calculator
Standard research pen format: 3 mL total volume, 300 clicks per pen. That’s fixed — so the only thing that changes is how many mg are in your specific pen. mg per click = your pen’s mg ÷ 300.
Vial mode: most research peptide vials are 3 mL borosilicate glass (industry standard — about 99% of compounds ship in this size). Larger compounds like NAD+ or high-mg GHK-Cu sometimes come in 5–10 mL vials. The bacteriostatic water you add must fit inside your physical vial — for a standard 3 mL vial, that’s usually 1–3 mL of BAC water. Tell us the vial’s peptide content (in mg), the BAC water you added, and your target dose — we work out the concentration, the volume to draw, and the syringe units on a U-100 insulin syringe.
Research and educational purposes only. Not medical advice. Not for human consumption. This calculator performs volumetric mathematics on the values you enter; it does not recommend doses. Compounds listed are not licensed as medicines for human use unless stated otherwise.
About MOTS-c
MOTS-c is a 16-amino-acid peptide encoded within the mitochondrial genome — one of a small number of mitochondrial-derived peptides identified in research literature. It is supplied as a research-grade compound for laboratory study and is unscheduled under the UK Misuse of Drugs Act 1971.
Published research literature describes MOTS-c in metabolic, insulin-sensitivity, exercise-performance, and longevity research contexts.
Typical reconstitution / pen formats
| Format | BAC water | Concentration / mg per click | Volume to draw / clicks | For |
|---|---|---|---|---|
| 10mg vial | 2 mL BAC water | 5.0 mg/mL | 1.0 mL (100 units U-100) | for a 5mg administration |
| 40mg pen (prefilled, 3ml/300 clicks) | — | 0.133 mg/click | ≈38 clicks for 5mg / ≈75 clicks for 10mg | industry-standard format |
MOTS-c dosing observed in research literature
Reported research-literature dose ranges for MOTS-c fall predominantly in the 5–10mg range per administration, typically administered subcutaneously two to three times per week.
These figures are reported here for completeness of the research-literature picture and do not constitute a dosage recommendation.
Half-life and frequency
Reports of MOTS-c serum half-life vary in published research; multi-day administration intervals are commonly described.
Storage and shelf life
Lyophilised refrigerated; reconstituted approximately 28 days refrigerated.
Frequently asked questions
How is MOTS-c typically dosed in research?
Published research protocols commonly describe 5–10mg per administration, two to three times per week, subcutaneous route.
How many clicks on a 40mg MOTS-c pen for a 5mg dose?
40mg ÷ 300 clicks = 0.133mg per click. For 5mg: 5 ÷ 0.133 ≈ 38 clicks.
Is MOTS-c legal in the UK?
Unscheduled, supplied as research-grade. Not licensed as a medicine in the UK.
Related compounds and stacks
Where to source research-grade MOTS-c
For UK readers researching MOTS-c, our partner supplier stocks research-grade preparations. (Partner link to be added after the affiliate arrangement is signed.) We do not sell peptides ourselves and are not responsible for any third-party supplier’s product quality, regulatory compliance, or customer service.
Compliance: Stackcalc.co.uk provides calculator tools and information for research and educational purposes only. We do not sell, supply, or recommend peptides, nootropics, or any other compounds. Content on this site does not constitute medical advice. Always consult a qualified healthcare professional. Not for human consumption.