Use this calculator to work out reconstitution volumes and per-injection draw amounts for KPV. Enter your vial size, the amount of bacteriostatic water you’ve added, and your target dose — the calculator returns the exact volume in mL, the syringe units to draw to, the concentration of your reconstituted solution, and the number of doses your vial contains.
For research and educational purposes only. This calculator performs volumetric maths on the values you enter; it does not recommend doses or provide medical advice.
Dose calculator
Standard research pen format: 3 mL total volume, 300 clicks per pen. That’s fixed — so the only thing that changes is how many mg are in your specific pen. mg per click = your pen’s mg ÷ 300.
Vial mode: most research peptide vials are 3 mL borosilicate glass (industry standard — about 99% of compounds ship in this size). Larger compounds like NAD+ or high-mg GHK-Cu sometimes come in 5–10 mL vials. The bacteriostatic water you add must fit inside your physical vial — for a standard 3 mL vial, that’s usually 1–3 mL of BAC water. Tell us the vial’s peptide content (in mg), the BAC water you added, and your target dose — we work out the concentration, the volume to draw, and the syringe units on a U-100 insulin syringe.
Research and educational purposes only. Not medical advice. Not for human consumption. This calculator performs volumetric mathematics on the values you enter; it does not recommend doses. Compounds listed are not licensed as medicines for human use unless stated otherwise.
Calculator preset shown: KLOW stack (KPV + GHK-Cu + BPC-157 + TB-500). For KPV mono-dosing maths, use the universal calculator at /calculator/. KPV standalone preset coming to the picker shortly.
About KPV
KPV is a tripeptide consisting of the three C-terminal amino-acid residues — lysine, proline, and valine — of alpha-melanocyte-stimulating hormone (alpha-MSH). It is sold internationally as a research-grade compound for laboratory study and is not licensed as a medicine in the UK or any other jurisdiction.
In research literature, KPV has been examined across studies relating to inflammatory signalling pathways, gastrointestinal cell biology, and dermatological research models. A summary of the published research is collected in the references section at the bottom of this page, with links to PubMed where available. This page does not interpret those studies for human application.
KPV is unscheduled under the UK Misuse of Drugs Act 1971. It is not approved for human consumption.
Typical reconstitution choices
For a 5mg KPV vial, common bacteriostatic water volumes give:
| BAC water added | Concentration | Volume per 500mcg dose | Insulin syringe units (U-100) |
|---|---|---|---|
| 1 mL | 5 mg/mL | 0.10 mL | 10 units |
| 2 mL | 2.5 mg/mL | 0.20 mL | 20 units |
| 3 mL | 1.67 mg/mL | 0.30 mL | 30 units |
| 5 mL | 1 mg/mL | 0.50 mL | 50 units |
For a 10mg KPV vial:
| BAC water added | Concentration | Volume per 500mcg dose | Insulin syringe units (U-100) |
|---|---|---|---|
| 1 mL | 10 mg/mL | 0.05 mL | 5 units |
| 2 mL | 5 mg/mL | 0.10 mL | 10 units |
| 3 mL | 3.33 mg/mL | 0.15 mL | 15 units |
| 5 mL | 2 mg/mL | 0.25 mL | 25 units |
A widely-chosen reconstitution for KPV is 5mg vial + 2mL BAC water = 2.5 mg/mL, giving a 20-unit draw on a U-100 insulin syringe for a 500mcg target dose.
KPV dosing observed in research literature
Reported research-literature dose ranges for KPV vary widely across administration routes. In subcutaneous animal-research administration, doses in the 100–1000 mcg per administration range are most commonly described. Oral administration of KPV also appears in published research literature — KPV is reported in literature to retain stability across oral and subcutaneous research administration routes.
These figures are reported here for completeness of the research-literature picture and do not constitute a dosage recommendation. Human dosing protocols for KPV are not established and KPV is not licensed for human use.
Half-life and frequency
The serum half-life of KPV in subcutaneous administration is short — typically reported in single-digit hours in animal studies. Daily research administration patterns are most commonly described in the literature for this reason.
Storage and shelf life
- Lyophilised (powder) vial, unopened: stable at refrigerator temperature (2–8°C) for 24 months or longer. Long-term storage at -20°C is reported as suitable.
- Reconstituted with bacteriostatic water: typically stable refrigerated (2–8°C) for approximately 28 days. The 0.9% benzyl alcohol in BAC water provides bacteriostatic action that gives reconstituted peptides their multi-week shelf life.
- Reconstituted with sterile water (not bacteriostatic water): stable refrigerated for only 24–48 hours.
- Freeze-thaw: repeated freeze-thaw cycles are not recommended for reconstituted research peptides.
Frequently asked questions
Q: What is KPV?
A: KPV is a tripeptide — lysine-proline-valine — corresponding to the three C-terminal amino-acid residues of alpha-melanocyte-stimulating hormone (alpha-MSH). It is sold as a research-grade compound and is not licensed for human use.
Q: How do I reconstitute a 5mg KPV vial?
A: A widely-described research reconstitution is 2 mL of bacteriostatic water for a 5mg vial, giving a concentration of 2.5 mg/mL. For a 500mcg target dose this gives a 20-unit draw on a U-100 insulin syringe.
Q: Can KPV be taken orally?
A: Oral administration of KPV is described in published research literature alongside subcutaneous administration. KPV is reported in literature to retain stability across both research administration routes. No human administration route is established or licensed.
Q: How long does KPV last after reconstitution?
A: Approximately 28 days refrigerated when reconstituted with bacteriostatic water. With sterile water (no preservative), only 24–48 hours.
Q: What syringe should I use for KPV?
A: U-100 insulin syringes (1 mL marked to 100 units) are standard for the small volumes involved in KPV research. A 30-gauge × 8mm needle is typical for subcutaneous research administration in animal studies.
Q: Is KPV legal in the UK?
A: KPV is not a controlled substance under the UK Misuse of Drugs Act 1971. It is sold as a research-grade compound for laboratory use only. It is not licensed by the MHRA as a medicine and is not approved for human consumption.
Q: Is KPV the same as BPC-157?
A: No. They are different peptides. BPC-157 is a 15-amino-acid synthetic peptide derived from a gastric-juice sequence. KPV is a 3-amino-acid fragment of alpha-MSH. Both appear together in the KLOW research stack alongside GHK-Cu and TB-500. See the KLOW Stack page for the combined calculator.
Q: How do I convert mg to mcg for KPV dosing?
A: 1 mg = 1,000 mcg. So a 500mcg dose is 0.5 mg, and a 1000mcg dose is 1 mg.
Q: Does KPV need to be refrigerated?
A: Yes. Both unopened lyophilised vials and reconstituted solution should be stored refrigerated at 2–8°C. Long-term unopened storage at -20°C is also suitable.
Research literature references
The following peer-reviewed publications are commonly cited in KPV research and provide entry points into the published literature. Stackcalc.co.uk does not interpret these studies for human application — they are listed for readers conducting their own research.
- Dalmasso G et al., “PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation”, Gastroenterology — PubMed
Related compounds and stacks
- GHK-Cu → — co-component of the KLOW stack alongside KPV; matrix-research category.
- BPC-157 → — co-component of the KLOW stack; tissue-repair-signalling research category.
- TB-500 → — co-component of the KLOW stack; tissue-repair-signalling research category.
- KLOW Stack → — KPV + GHK-Cu + BPC-157 + TB-500 multi-compound calculator.
Where to source research-grade KPV
For UK readers researching KPV, our partner UK supplier stocks research-grade KPV vials. Stackcalc.co.uk has a partner arrangement; visitors using our partner link receive a discount code at checkout (terms detailed on the partner site).
We do not sell peptides ourselves. The partner link is provided as a convenience to readers who have asked where to source research-grade compounds. Stackcalc.co.uk is not responsible for any third-party supplier’s product quality, regulatory compliance, or customer service — verify the supplier’s terms and conduct your own due diligence before any purchase.
(Partner link to be added after the affiliate arrangement is signed — held back deliberately pending the partner agreement.)